Case A 44-year-old Nigerian man was admitted as an emergency while visiting relatives in England. His symptoms include a

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Case A 44 Year Old Nigerian Man Was Admitted As An Emergency While Visiting Relatives In England His Symptoms Include A 1 (49.64 KiB) Viewed 34 times

Case A 44-year-old Nigerian man was admitted as an emergency while visiting relatives in England. His symptoms include abdominal pain, sweating, rigors and vomiting. Had been treated twice for malaria but had never taken malarial prophylaxis. Examination revealed he is ill and jaundiced, temperature of 39.2°C, blood pressure was 90/70, but no signs of visceral perforation. Differential diagnosis include-occult gastrointestinal bleeding, septicaemia, hepatitis or recurrence of malaria Emergency investigations: normal haemoglobin (140g/l), white cell count of 6.1 x 109/l, sickle-cell anaemia (excluded), thick blood film Treatment: intravenous quinine. Unfortunately the Px rapidly deteriorated over the next 30h leading to cardiac arrest. Post-mortem diagnosis: Cerebral Malaria Case Study Questions 1. What is your final diagnosis here? Explain the cause of his disease. 2. What drug, dosage form, schedule, and duration of therapy are best for treating patients with this condition?