HCHÖNHCH- & NIG 1. BrCN 2. H₂O NGHENIGH ON HNCC R CH₂ R' R CH₂ R' CH₂-S-CH₂ CH₂-OH Proteins can be cleaved specifically
Posted: Fri May 06, 2022 7:35 am
HCHÖNHCH- & NIG 1. BrCN 2. H₂O NGHENIGH ON HNCC R CH₂ R' R CH₂ R' CH₂-S-CH₂ CH₂-OH Proteins can be cleaved specifically at the amide bond on the carboxyl side of methionine residues by reaction with cyanogen bromide (above). C by a four-stage mechanism. The third stage is an hydrolysis reaction that cleaves the peptide chain. At the end of this stage, the carts former methionine becomes part of a lactone (cyclic ester) ring. Draw curved arrows for the step that cleaves the peptide chain. Arrow-pushing Instructions X :0: :OH 0: Ở NHCHC NHCH CHÍNH, CHO 0-H - R H₂C LO: R' H -NHCHC -