7. Qinghaosu ((+-Artemisinin, +%*) for treatment of malaria was isolated from qinghao by Youyou Tu (#) in the early 1970
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7. Qinghaosu ((+-Artemisinin, +%*) for treatment of malaria was isolated from qinghao by Youyou Tu (#) in the early 1970
7. Qinghaosu ((+-Artemisinin, +%*) for treatment of malaria was isolated from qinghao by Youyou Tu (#) in the early 1970's. A total synthesis of Qinghaosu (9) is shown below (J. Am. Chem. Soc., 1992, 114,974). Provide the reagent(s), for steps b, c, e and g. (8 marks) Alkaline NO THIP 42LDA, HMIT, THP, he? ܙܚܗܐܦ Me,SI), ALBO Bd.1c thea A, DMAP | 1.poyo,non, కు Messi 1.3LDEA, THE -78 to 50°C thea 2 LDA Oso 45°C Mel, -78 to 25 °C 0, 0, 0 - 0 BHT, SOMH SO [•] - Messi WH HO- 7
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