Invega tablets (12 mg paliperidone) are indicated for the schizophrenia, including acute treatment and recurrence preven

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Invega tablets (12 mg paliperidone) are indicated for the
schizophrenia, including acute treatment and recurrence
prevention.
1. Outline TWO disadvantages of this medicine compared with
immediate release tablet. [2 marks]
2. Discuss the design of Invega tablets (12 mg paliperidone)
identifying and describing the properties of TWO excipients used to
modify the release of the drug from the tablet. [4 marks]
3. Construct a suitable plasma concentration-time plot for the
Invega tablets (12 mg paliperidone) and label the different
components and areas in the graph. [4 marks]
4. Outline FOUR steps to describe how drug is released from the
tablets including any diffusion process. [2 marks]