Case 3 Oscar T. a 45-year-old male from the Midwest presented with the following symptoms during February: weakness, fat

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Case 3 Oscar T A 45 Year Old Male From The Midwest Presented With The Following Symptoms During February Weakness Fat 1 (54.45 KiB) Viewed 18 times

Case 3 Oscar T. a 45-year-old male from the Midwest presented with the following symptoms during February: weakness, fatigue, orthostatic hypotension, weight loss, dehydration, and decreased cold tolerance. His blood chemistry values follow: • Serum sodium 128 mEq/L (normal = 135-146 mEg/L) • Serum potassium 6.3 mEq/L (normal = 3.5-5 mEq/L) • Fasting blood glucose 65 mg/dL (normal = 65-100 mg/dL) Hematology tests resulted in the following values: Hematocrit 50% (normal is 42-52%); Leukocytes 5000/cu mm (normal is 4300-10800/ cu mm) Oscar also noticed increased pigmentation (tanning) of both exposed and nonexposed portions of the body and back. A plasma cortisol determination indicated a low cortisol level. Following administration of ACTH, plasma cortisol did not rise significantly after sixty and ninety minutes. Endogenous circulating levels of ACTH were later determined to be significantly elevated. el ****** -MEN 7. MILE 10. Why is Oscar's endogenous circulating level of ACTH significantly elevated? 11a. What is the cause of Oscar's hyperpigmentation? 11b. How is hyperpigmentation related to his high levels of ACTH? 12. What type of replacement therapy would be required for Oscar? Will the replacement of one hormone suffice to treat all his symptoms? Am sulna dicaudam nuttnat f 30?