Which of the following is most likely to cause a genetic change in a cell leading to the start of multi-step tumorigenes

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answerhappygod
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Which of the following is most likely to cause a genetic change in a cell leading to the start of multi-step tumorigenes

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Which of the following is most likely to cause a genetic changein a cell leading to the start of multi-step tumorigenesis?
a promoter agent
an initiator agent
a stem cell
an NSAID
none of the above
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