2. Glucose oxidase and determination of blood glucose. The enzyme glucose oxidase isolated from the mold Penicullium not

Business, Finance, Economics, Accounting, Operations Management, Computer Science, Electrical Engineering, Mechanical Engineering, Civil Engineering, Chemical Engineering, Algebra, Precalculus, Statistics and Probabilty, Advanced Math, Physics, Chemistry, Biology, Nursing, Psychology, Certifications, Tests, Prep, and more.
Post Reply
answerhappygod
Site Admin
Posts: 899603
Joined: Mon Aug 02, 2021 8:13 am

2. Glucose oxidase and determination of blood glucose. The enzyme glucose oxidase isolated from the mold Penicullium not

Post by answerhappygod »

2. Glucose oxidase and determination of bloodglucose. The enzyme glucose oxidase isolated from themold Penicullium notatum catalyzes the oxidationof beta-D-glucose into a lactone. This enzyme is highly specificfor the beta anomer of glucose and does not affect the alphaanomer. In spite of this specificity, the reaction catalyzed byglucose oxidase is commonly used in clinical tests for total bloodglucose, which contain a mixture of alpha and betaD-glucose.
What are the circumstances that make it possible for the use ofglucose oxidase in measuring total blood glucose? Why is this avalid test even though glucose oxidase only binds to the betaanomer of D-glucose?
Join a community of subject matter experts. Register for FREE to view solutions, replies, and use search function. Request answer by replying!
Post Reply