A middle-aged man from East Africa, who had immigrated to the United States three years ago, had an intermittent fever f

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A Middle Aged Man From East Africa Who Had Immigrated To The United States Three Years Ago Had An Intermittent Fever F 1 (51.05 KiB) Viewed 57 times

A Middle Aged Man From East Africa Who Had Immigrated To The United States Three Years Ago Had An Intermittent Fever F 2 (36.17 KiB) Viewed 57 times

A middle-aged man from East Africa, who had immigrated to the United States three years ago, had an intermittent fever for two weeks which progressed to a daily fever with chills. He had also experienced severe weight loss during the previous 6 months. He had traveled to Southeast Asia while living outside the United States, and his past medical history revealed that he had contracted malaria twice. A CT scan revealed that he had an enlarged spleen and liver. A needle biopsy of the spleen was sent to the laboratory for analysis. The stained preparation is shown below. 96 1. What parasite do you suspect? A. Ancylostoma braziliense B. Dracunculus medinensis C. Leishmania donovani D. Onchocerca volvulus 20μm
2. How could the patient have acquired this infection? A. Bite of Phlebotomus spp. (sandfly) B. Bite of Glossina spp. (tsetse fly) C. Bite of Lutzomyia spp. (sandfly) D. Transfer of the infective form into an open wound 3. Which of the following disease manifestations does NOT occur if this infection progresses beyond the cutaneous stage? A. Amastigote forms are found in the bone marrow B. Daily double-spiking fever C. Promastigote forms are found in the blood D. L.D. forms are found in the liver and spleen macrophages 4. What is/are the primary characteristic(s) in order to differentiate and identify this organism? A. Giemsa stain B. Culture in NNN medium C. Serologic techniques using monoclonal antibodies D. All of these laboratory tests are needed