Based solely on the data provided below, do you think that a 200 mg dose provides adequate unbound drug concentrations i

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answerhappygod
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Based solely on the data provided below, do you think that a 200 mg dose provides adequate unbound drug concentrations i

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Based solely on the data provided below, do you think that a 200mg dose provides adequate unbound drug concentrations in theplasma?
200mg, twice daily,
Cmax 8.4 mg/L
Plasma protein binding = 98.8%, Solubility = 0.0381 mg/mL
MW = 472.6
Log P = 4.8, pKa = 9.9
Compound = Pacritinib **may want to look up structure ofcompound, this is its name**
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