216 NOTES 3. As a children's medicine, Tylenol has a major marketing advantage over aspirin: Liquid Tylenol preparations

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216 Notes 3 As A Children S Medicine Tylenol Has A Major Marketing Advantage Over Aspirin Liquid Tylenol Preparations 1 (35.72 KiB) Viewed 55 times

216 NOTES 3. As a children's medicine, Tylenol has a major marketing advantage over aspirin: Liquid Tylenol preparations (essentially, Tylenol dissolved in flavored water) are stable, whereas comparable aspirin solutions are not. Aspirin has a phenyl ester func- tionality. When this ester bond is subjected to water for prolonged periods of time, it hydrolyzes to the carboxylic acid and a phenol derivative. Write the structures of all products. 4. Pure aspirin has a melting point of 135-136°C. If aspirin crystals were not completely dried before the m.p. was determined, what effect could this have on the observed melting point? 5. Sketch the setup for a vacuum filtration of isolated crystals after extraction from an analgesic drug. Label all parts.