Given the following scenarios, which receptor/ligandcombination (provide specific examples) must be at work tocause:
a. A spike in cAMP-dependent kinasesignaling?
b. An activation ofphosphodiesterase-type-5-mediated smooth musclerelaxation?
c. A spike in intracellularCa++?
d. Activation of MAP-kinase-mediatedtranscriptional activity?
e. A particular drug provide growthsenescence by acting on membrane receptors to inhibitmitogen-activated protein transcription
f. A particular drug inhibitsskeletal muscle depolarization/contraction by binding to andinhibiting a membrane receptor
g. A particular drug blocks painsignals by inhibiting metabotropic receptors in the central nervoussystem
Given the following scenarios, which receptor/ligand combination (provide specific examples) must be at work to cause: a
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