The questions below refer to the diagram. Protein X is a putative regulator of cell polarity. Epithelium Mum Protein X w

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The Questions Below Refer To The Diagram Protein X Is A Putative Regulator Of Cell Polarity Epithelium Mum Protein X W 1 (313.47 KiB) Viewed 35 times

The questions below refer to the diagram. Protein X is a putative regulator of cell polarity. Epithelium Mum Protein X wun 200 d Microfilaments Microtubules Nucleus ER Protein X EMT MET Protein X a. What does EMT and MET refer to in this diagram? Are these usually reversible states? What transition in cell polarity states does it involve? What processes are EMT and MET involved in during the lifespan of a human? (4 marks) b. During the EMT process, for a cell to migrate through a tissue, what must it do to the ECM? What enzymes are used to achieve this? (2 marks) c. Could Protein X be E-Cadherin? Explain your reasoning. (2 marks) d. If Protein X was a member of the Scribble complex, would its role be upstream or downstream from integrin signalling in directed migration? What would you expect the effect of the loss of function of Protein X be on microtubule organisation during directed migration? (2 marks)