A 62-year-old man comes to the physician because of a 1-week history of muscle cramps accompanied by painful spasms in h

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A 62-year-old man comes to the physician because of a 1-week history of muscle cramps accompanied by painful spasms in his arms and legs He tells the physician that, for the past 4 months, he has had trouble opening jars and using silverware. Examination shows muscle weakness and exaggerated deep tendon reflexes. An appropriate treatment of the muscle cramps and spasms in this patient includes systemic administration of a drug with which of the following mechanisms of action?


A. Agonist at v-aminobutyric acid B (GABAs) receptors
B. Antagonist at glycine receptors
C. Blockade of acetylcholine release from nerve terminals
D. Inhibition of the norepinephrine transporter
E. Inverse agonist at benzodiazepine receptors