Furosemide In dogs, oral bioavailability is approximately 77%. It has a rapid onset of action, 5 minutes IV and 30 minut

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Furosemide In Dogs Oral Bioavailability Is Approximately 77 It Has A Rapid Onset Of Action 5 Minutes Iv And 30 Minut 1 (69.29 KiB) Viewed 11 times

Furosemide In dogs, oral bioavailability is approximately 77%. It has a rapid onset of action, 5 minutes IV and 30 minutes IM. In the dog when administered IV, PO, SQ, the urine output peaked at 1 br. (IV), 2 hours (PO) and 1 br. (SQ) and returned to baseline levels at 2,4 and 6 hours respectively. Duration of action is 3-6 hours. The drug is approximately 95% bound to plasma protein in both azotemic and normal patients. The serum half-life is 2 hours but prolonged in patients with CKD, uremia, CHF and neonates. Answer the following questions 8. 9. 10. 11. disease? What is the veterinary trade name of this drug? What class of drug is furosemide? a. 14. What would you advise the owners regarding taking the dog out? Would the veterinarian decrease the dose in an animal with concurrent renal 12. If the drug serum concentration was 8 mg/dl, at 10 AM., what would the concentration be at 4 PM? 13. When given concurrently, which drug, furosemide or pimobendan are more likely to have a higher serum concentration than if given alone? Why? What is a potentially severe side effect of furosemide other than dehydration?