Using the complex structure of the almost identical Mpro from SARS-CoV-1 with a C145A mutation (PDB: 5B6O), describe how

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Using the complex structure of the almost identical Mpro fromSARS-CoV-1 with a C145A mutation (PDB: 5B6O), describe howSARS-CoV-2 Mpro recognises a sequence in the SARS-CoV-2polyproteins. Superpose the two proteases and label the subsites(S1, S2, S1’ and S2’). 2. SARS-CoV-2 Mpro has been co-crystallisedwith numerous inhibitors. Select one such complex and describe howthe inhibitor binds the protease.