A peptide has the following sequence: GSLRPEE pKa values of the peptide side chains, terminal amino groups, and terminal

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A Peptide Has The Following Sequence Gslrpee Pka Values Of The Peptide Side Chains Terminal Amino Groups And Terminal 1 (66.71 KiB) Viewed 12 times

A peptide has the following sequence: GSLRPEE pKa values of the peptide side chains, terminal amino groups, and terminal carboxyl groups are provided in the table below... Amino acid Amino pK₁ Carboxyl pKa Side-chain pKa glutamate 9.60 2.34 4.25 histidine 9.17 1.82 6.00 9.39 2.38 9.15 2.21 9.60 2.34 9.60 2.36 9.04 2.17 10.96 1.99 tryptophan serine glycine leucine arginine proline 12.48 a) What is the net charge of the peptide at pH 3? List which group(s) carry a positive charge at this pH and which group(s) carry a negative charge at this pH. b) What is the net charge of the peptide at pH 8? List which group(s) carry a positive charge at this pH and which group(s) carry a negative charge at this pH. c) What is the net charge of the peptide at pH 11? List which group(s) carry a positive charge at this pH and which group(s) carry a negative charge at this pH.