Refer to the Biochemistry in Focus section of your text for this chapter to answer this question. A mutation in hyperpol
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Refer to the Biochemistry in Focus section of your text for this chapter to answer this question. A mutation in hyperpol
question. A mutation in hyperpolarization-activated cyclic nucleotide-gated, or HCN, channels results in decreased heart rate. These mutant HCN channels require greater hyperpolarization of membrane than the wild-type to open, thus resulting in slower depolarization at resting potential. Choose the statement that describes the cause of slower depolarization of the mutant HCN channels at resting potential. At resting potential, fewer mutant HCN channels are open. Therefore, fewer potassium ions flow into the cell, resulting in slower depolarization. At resting potential, fewer mutant HCN channels are open. Therefore, fewer sodium ions flow into the cell, resulting in slower depolarization. At resting potential, more mutant HCN channels are open. Therefore, more sodium ions flow out of the cell, resulting in slower depolarization. At resting potential, more mutant HCN channels are open. Therefore, more potassium ions flow out of the cell, resulting in slower depolarization. Incorrect
Refer to the Biochemistry in Focus section of your text for this chapter to answer this