2. Which of the following is/are TRUE about mouse embryonic stem (ES) cells and knockout mice? (A) One can “knock out” a
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2. Which of the following is/are TRUE about mouse embryonic stem (ES) cells and knockout mice? (A) One can “knock out” a
2. Which of the following is/are TRUE about mouse embryonic stem(ES) cells and knockout mice?(A) One can “knock out” a gene in specific tissues or organsonly.(B) Knockout mice are generated by injecting ES cells into themouse uterus.(C) ES cells proliferate very fast and can differentiate intodifferent cell types both in vitro and in vivo.(D) The targeting construct can include genes for both positiveselection and negative selection.