Human Immunodeficiency virus (HV) infects cats that have both CD4 and CCRS cal surface molecules. The veal nucleic and m

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Human Immunodeficiency Virus Hv Infects Cats That Have Both Cd4 And Ccrs Cal Surface Molecules The Veal Nucleic And M 1 (23.62 KiB) Viewed 13 times

Human Immunodeficiency Virus Hv Infects Cats That Have Both Cd4 And Ccrs Cal Surface Molecules The Veal Nucleic And M 2 (33.05 KiB) Viewed 13 times

Human Immunodeficiency Virus Hv Infects Cats That Have Both Cd4 And Ccrs Cal Surface Molecules The Veal Nucleic And M 3 (33.05 KiB) Viewed 13 times

Human Immunodeficiency virus (HV) infects cats that have both CD4 and CCRS cal surface molecules. The veal nucleic and molecules are enclosed in a protein coped, and the protein capsid is to contained in envelope consisting of a lipid bilayer membrane and val glycoproteins. One hypothes for viral entry into certs is that binding of HIV membri plasma membrane, releasing the viral capsid into the cytoplam An athemative hypothesis is that HIV gains entry into the cell these shamative hypotheses for HV eroy, researchers labeled the spids on the HIV membrane with a red forescent de glycoproteine to CD4 and CCRS nefes fusion of the HIV ated endocytoes and membrane tusion occurs in the endocytrice T Glycoprotein Viral envelope Reverse transcriptase Capsid RNA (two identical strands) HIV What would be observed by live-call fuorescence inroscopy immediately after HIV any HIV anters the cat by endocytosis frat, and then lart with the yea A spot of red furescence will remain outside the cell aherving the vid OA spt of ducence will diffuse in the infected cytoplasm A spot of red france will be able on the infected call's plasma membrane, making the site of membrane fusion and Vary The red fluorescent tye-labeled pide will appear in the infected ces
Human immunodeficiency virus (HIV) infects cells that have both CD4 and CCR5 cell surface molecules. The viral nucleic acid molecules are enclosed in a protein capsid, and the protein capsid is itself contained inside an envelope consisting of a lipid bilayer membrane and viral glycoproteins. One hypothesis for viral entry into cells is that binding of HIV membrane glycoproteins to CD4 and CCRS initiates fusion of the HIV membrane with the plasma membrane, releasing the viral capsid into the cytoplasm. An alternative hypothesis is that HIV gains entry into the cell via receptor-mediated endocytosis, and membrane fusion occurs in the endocytotic vesicle. To test these alternative hypotheses for HIV entry, researchers labeled the lipids on the HIV membrane with a red fluorescent dye. Glycoprotein Viral envelope go Los bbbb Reverse transcriptase HIV -Capsid RNA (two identical strands) What would be observed by live-cell fluorescence microscopy immediately after HIV entry if HIV enters the cell by endocytosis first, and then later fuses with the endocytotic vesicle membrane? A spot of red fluorescence will remain outside the cell after delivering the viral capsid. A spot of red fluorescence will diffuse in the infected cel's cytoplasm A spot of red fluorescence will be visible on the infected cell's plasma membrane, marking the site of membrane fusion and HIV entry. The red fluorescent dye-labeled lipids will appear in the infected cell's interior.