Initial scenario Clinton is a 40-year-old African-American man, married with 4 children, who works as a foreman of a loa

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Initial scenario
Clinton is a 40-year-old African-American man, married with 4children, who works as a foreman of a loading dock. He wasdiagnosed with T2DM 3 months ago. He weighs 220.5 lb and has a bodymass index (BMI) of 31.6 kg/m2. He is a current smoker. He is on noprescription medications. His current A1C level is 7.8%. His totaland LDL cholesterol concentrations are above normal. He complainsof sleep disturbance. His vitals: pulse: 55 bpm, respirations:22/min, BP: 148/92 mmHg.
Before answering question 4, review the following scenarioupdate.
Scenario update
Clinton is started on the following medications:
Clinton is counseled on his therapeutic targets for reducing therisks of diabetes complications:
Clinton understands that he must stop smoking and is referred toa smoking cessation program. He is referred to a registereddietitian for nutrition counseling. He agrees to begin walking 15minutes a day after dinner with his wife. He is counseled on thefact that diabetes is a progressive disease, that his medicationswill change over time, and that these changes will discussed withhim.
Three months later:
Clinton has reduced smoking to two packs/week. He thinks he hasgained weight because he is using hard candy and chewing gum inplace of cigarettes.
You explain to Clinton that two classes of anti-diabetic agentsdo not cause weight gain; at the moment, he prefers an oral agent,explaining that he has a lot going on with his efforts andlifestyle modification, including smoking cessation, as well astrying to get his family to work with him to change their mealhabits.
4. While you are willing to work with Clinton on thisand revisit the situation at his next 3-month visit, you tell himthat GLP-1 RAs have which of the following effects that DPP-4inhibitors don't?
Choose all that apply.
I. Can cause slow, steady weight loss
II. Decrease glucagon secretion
III. Enhance feelings of fullness
IV. Increase insulin secretion
V. Slow gastric emptying