Question 3 (Mandatory) (10 points) The concentration of fructose-2,6 bisphosphate (F 2,6 BP) is controlled by phosphofru
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Question 3 (Mandatory) (10 points) The concentration of fructose-2,6 bisphosphate (F 2,6 BP) is controlled by phosphofru
Question 3 (Mandatory) (10 points) The concentration of fructose-2,6 bisphosphate (F 2,6 BP) is controlled by phosphofructokinase-2 (PFK-2) and fructose bis phosphatase-2 enzymes (FBPase-2). (a) F 2,6 BP is an allosteric modulator of two important enzymes: one in glycolysis and another in gluconeogenesis. Name these enzymes. (4 pts) (b) Which hormone leads to the activation of PFK-2? (4 pts) (c) Activation of PFK-2 will lead to higher concentrations F2,6 BP. How does this affect two enzymes in (a)? Activate or inactivate? How is this consistent with the metabolic needs of the cell according to the hormone in (b)? (4 pts) Question 4 (Mandatory) (8 points) Answer the following questions regarding glycogen metabolism: (A) Name two enzymes needed for the removal of multiple monomers from Glycogen and their conversion into Glucose-6-Phosphate (4 pts) (B) What are two metabolic paths that Glucose-6-phosphate can take? (4 pts) I 14