22. Calculation of the pH of a Solution of a Polyprotic Acid Histidine has ionizable groups with pk, values of 1.8, 6.0,

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22 Calculation Of The Ph Of A Solution Of A Polyprotic Acid Histidine Has Ionizable Groups With Pk Values Of 1 8 6 0 1 (28.7 KiB) Viewed 69 times

22. Calculation of the pH of a Solution of a Polyprotic Acid Histidine has ionizable groups with pk, values of 1.8, 6.0, and 9.2, as shown below (His imidazole group). A biochemist makes up 100 mL of a 0.100 M solution of histidine at a pH of 5.40. She then adds 40 mL of 0.10 M HCI. What is the pH of the resulting solution? COOH L H₂N-CH 1 CH₂ H N H lonizable group CH COO™ I H₂N-CH 1.8 pk₁ CH₂ H -N -COOH-COO™ CH -HisH+ COO™ H₂N-CH 6.0 pK₂ CH₂ H -N H -His CH -NH3 COO™ H₂N-CH 9.2 pk3 CH₂ H N H -NH₂ CH