A sample from a 55-year-old white male donor demonstrated a positive antibody screen during routine processing testing.

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A Sample From A 55 Year Old White Male Donor Demonstrated A Positive Antibody Screen During Routine Processing Testing 1 (155.51 KiB) Viewed 37 times

A sample from a 55-year-old white male donor demonstrated a positive antibody screen during routine processing testing. The antibody identification panel's results are shown. The laboratory uses LISS as an antibody enhancement and anti-IgG for the AHG reagent. Refer to the panel to answer the following questions: Rh MNS P1 Lewis Lutheran ke Cell DC Ecef CWMNS SP1 Lea Leb Lua Lub K 1 R1R1 (51) + + 0 0 + 0 0 + + + + + 0 + 0 + 2. + + 0 0 + 0 + + 0 0 + + 0 + 0 + O R1R1 (32) 3 R2R2 + 0 + + 0 0 0 0 + 0 + + + + 0 0 (64) + + 4r"r (75) 0 0 + + + + 0 + 0 + 0 + 0 + 0 + 0 5 rr (87) 000+ + + + + + + + 0 + 0 + O 6 rr 000 + + + + + + + + + 0 0 + 0 - o o (98) 7 RORO 0 + + 0 0 + + + 0 + 0 0 0 0 0 + 0 (76) + + 8 rr (53) 0 0 0 + + + 0 + 0 + + + 0 0 0 + 0 + 0 9 rr (23) 000 + + + + + + 0 0 + 0 0 + O 10 R1R1 (34) + + 0 0 + 0 + 0 + 0 + + 0 + 0 + 0 Patient Cells 1. What phase in the panel is showing antibody reactivity? 2. What does this reaction phase suggest regarding the immunoglobulin class of antibody? 3. Is this antibody an alloantibody or an autoantibody? Defend your answer.