A pharmacokinetic experiment was performed by a drug company and showed that Drug A has a greater volume of distribution

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A pharmacokinetic experiment was performed by a drug company and
showed that Drug A has a greater volume of distribution than Drug
B. Which of the following can be deduced from the findings?
Drug A could possibly be tightly bound to plasma proteins
compared to Drug B.
Drug A is greatly bound to molecules in the peripheral tissues
compared to Drug B
Drug B would require a greater dose to be administered in order
to achieve measurable plasma concentrations compared to Drug A.
The diffusion of Drug A to peripheral tissues is limited
compared to that of Drug B.