Although the concentration of
glucose in the general circulation normally doesn’t rise much above
7 mM, the liver is exposed to much higher concentrations after a
meal. The intestine delivers glucose into the portal circulation,
which goes directly to the liver. In the portal circulation, the
concentration of glucose can be as high as 15 mM. At what fraction
of the maximum rate (Vmax) do liver cells import glucose
at this concentration?
C0=15 mM
Km= 15 mM
Vo->i= Vmax
15mM/15mM + 15 mM Vo->i=
Vmax 15mM/30 mM
Vo->i= 1/2 Vmax
The liver cells are importing glucose
at one half the maximum rate.
C. Do these calculations fit
with the physiological functions of brain and liver cells? Why or
why not?
Please answer C. The
calculation is 1/2 maximum rate
Although the concentration of glucose in the general circulation normally doesn’t rise much above 7 mM, the liver is exp
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