The average values of clearance and volume of distribution of
valproic acid in an adult population are 0.5 L/h and 9 L,
respectively. Use this data to answer the next two questions.
i) In an average adult, the expected concentration of
valproic acid 25 hours after 700 mg IV bolus injection is ______
mg/L ?
ii) In an average adult, the expected rate of
elimination of valproic acid right after the 700 mg IV bolus
injection is ______ mg/L ?
The average values of clearance and volume of distribution of valproic acid in an adult population are 0.5 L/h and 9 L,
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