Use the given then answer the following:
The population PK parameters for drug X are tabulated below.
When 25 mg of drug X. salt (S=0.8) was injected as an IV bolus
injection to a 50-kg patient, the resulting initial concentration
of drug X in the patent was 2 mg/L. The half-life of the drug in
the patient was 30 min.
i)The volume of distribution (V) of drug X in the
patient is ____ L?
ii)The expected amount of drug X excreted into urine
after 1 hour is _____ mg?
iii)The total area under the curve (AUG) of drug X in
the patient is _____ mg.min/L?
Thank you
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