Procedure: Measure 0.60 g of 2-naphthol into a 50 ml round bottom flask with a stir bar. Add 5.0 mL of absolute ethanol

Business, Finance, Economics, Accounting, Operations Management, Computer Science, Electrical Engineering, Mechanical Engineering, Civil Engineering, Chemical Engineering, Algebra, Precalculus, Statistics and Probabilty, Advanced Math, Physics, Chemistry, Biology, Nursing, Psychology, Certifications, Tests, Prep, and more.
Post Reply
answerhappygod
Site Admin
Posts: 899603
Joined: Mon Aug 02, 2021 8:13 am

Procedure: Measure 0.60 g of 2-naphthol into a 50 ml round bottom flask with a stir bar. Add 5.0 mL of absolute ethanol

Post by answerhappygod »

Procedure Measure 0 60 G Of 2 Naphthol Into A 50 Ml Round Bottom Flask With A Stir Bar Add 5 0 Ml Of Absolute Ethanol 1
Procedure Measure 0 60 G Of 2 Naphthol Into A 50 Ml Round Bottom Flask With A Stir Bar Add 5 0 Ml Of Absolute Ethanol 1 (75.04 KiB) Viewed 95 times
Procedure Measure 0 60 G Of 2 Naphthol Into A 50 Ml Round Bottom Flask With A Stir Bar Add 5 0 Ml Of Absolute Ethanol 2
Procedure Measure 0 60 G Of 2 Naphthol Into A 50 Ml Round Bottom Flask With A Stir Bar Add 5 0 Ml Of Absolute Ethanol 2 (20.47 KiB) Viewed 95 times
Procedure: Measure 0.60 g of 2-naphthol into a 50 ml round bottom flask with a stir bar. Add 5.0 mL of absolute ethanol and begin stirring to dissolve the 2-naphthol. Once the 2-naphthol has been suspended in solution add 3-5 pellets of sodium hydroxide, approximately 0.3 g total. After attaching a condenser, bring the mixture to temperature and reflux for 30 min using a hot water bath. CAUTION: Sodium hydroxide is caustic and can damage both the eyes and exposed skin, causing severe burns Once 30 minutes has elapsed allow the solution to briefly cool to 60°C. Once cool remove the condenser and add 0.60 ml of 1-bromobutane via syringe, reattach the condenser and reflux hd solution in the flask for 1 hour. Once the reaction is done refluxing allow to reach 50°C before adding a small amount of ice to the flask (2-5 g) and stir until the ice is completely melted. Allow the reaction to cool in an ice bath for 10 minutes to precipitate as much product as possible, adding a small amount of extra ice or Dl water to the flask if no precipitate is observed. Collect the product via vacuum filtration with a Bachner filter and wash with iced Dl water. After recording the mass of the product, obtain an H-NMR spectra for it using the 400 MHz NMR with the NMR technician's assistance. Also, perform a melting point determination on the crude product For the TLC take a small sample (I speck on the tip of a spatula, 2-6 mg) of the crude product and 2-naphthol and dissolve each in separate beakers or vials in a small amount (1 Pasteur pipette-ful) of ethyl acetate. Use separate glass capillary tubes to apply the two analyte solutions to the starting line of the TLC plate. Place the TLC plate in a beaker or jar with a shallow pool of 1:9 ethyl acetate hexane. Visualize using a UV lamp and collect measurements to calculate and compare R values Diagram 1: A is the product and B is the Starting material (2-naphthol)
3) (3 points] Explain why the formation of a side product ) doesn't occur from the use ethanol as our solvent in today's Williamson ether synthesis (Hint: think about the first step of the synthesis and the role of NaOH) 4) (3 points] Explain the two factors that cause the product to precipitate better with the addition of ice to the solution in today's experiment. (Review recrystallization in Pavia for more help)
Join a community of subject matter experts. Register for FREE to view solutions, replies, and use search function. Request answer by replying!
Post Reply