2. Answer ALL parts a) - f). In the biosynthesis of amino acids, two molecules of 3 are transformed into 4. OH a) State

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2 Answer All Parts A F In The Biosynthesis Of Amino Acids Two Molecules Of 3 Are Transformed Into 4 Oh A State 1 (57.75 KiB) Viewed 70 times

2. Answer ALL parts a) - f). In the biosynthesis of amino acids, two molecules of 3 are transformed into 4. OH a) State the name of 3 and the name of the biochemical pathway from which it is synthesised from glucose. [2] b) State the cofactor that is required in the transformation of 3 into 4 and briefly explain its role in the reaction. A curly arrow mechanism is not required. [3] c) Suggest one pathway for biochemical transformation of 5 into valine, indicating any other substrate(s), cofactor(s) and product(s). A curly arrow mechanism is not required. зво ⒸNH3 valine [4] d) Draw the structure of a dipeptide with the sequence Val-Ala. Label the peptide bond, N-terminus and C-terminus in your diagram. [4] e) Calculate the ratio of the concentration of the zwitterion form of valine to the concentration of the deprotonated anion, for an aqueous solution at pH 8.20. The pKa values of valine are 2.29 and 9.74. [5] f) Calculate the isoelectric point of an amino acid with three ionisable functional groups (pka1 = 1.94, pKa2 = 8.65, pKa3 = 10.76), showing your calculation. [2]