1. Define the term innate immunity 2. List several mechanisms of innate defense and give a brief description of each one

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1. Define the term innate immunity 2. List several mechanisms of innate defense and give a brief description of each one

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1. Define the term innate immunity 2. List several mechanisms of innate defense and give a brief description of each one 3. Identify the body's first line of defense 4. Describe chemotactic factors released from the mast cell 5. What is the function of interferon? 6. Define the following terms: antigens, antibodies, antigenic determinants, combining sites, clone 7. What two terms are synonyms for combining sites? 8. When an antigen-antibody complex is formed, what region on the antigen molecule fits what region on the antibody molecule? 9. Activated B cells develop into clones of what two kinds of cells? 10. What cells synthesize and secrete copious amounts of antibodies? 11. Explain the function of memory cells 12. Antibodies belong to what class of compounds? Diagram and describe the structure of an antibody 13. Explain the two basic tenets of Burnet's clonal selection theory 14. What are cytokines? Lymphotoxins? 15. Differentiate between the classifications of natural and artificial immunity. 16.Describe the process behind the functioning of modern vaccines. 17. What are monoclonal antibodies, and how do they function?
Critical Thinking Questions 1. The causative organism of tuberculosis has a coat around it that makes it much more resistant to other bacteria to digestive enzymes and hydrogen peroxide. What can you say about this characteristic, and why is it more difficult for the body to fight off these bacteria? 2. If a person had a mutation that prevented the formation of the complement proteins, what capabilities would be lessened in the immune system? 3. How would you explain how the various type of T cells can fine-tune the immune system? 4. Why do you think the development of cancer can be seen as a failure of the immune system? 5. Explain the distinction between inherited immunity and acquired immunity? 6. One of the best-known examples of acquired immune deficiency is acquired immune deficiency syndrome (AIDS). The human immunodeficiency virus (HIV)causes this syndrome. How would you summarize the mechanisms of HIV infection? 7. If the genes that produce Toll-like receptors (TLRs) were abnormal, what effect might that have on a person's immunity?
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