The lipid bilayer forming cell membranes behaves as a 2D fluid whose fluidity depends
largely on its lipid composition. Phospholipid molecules in the bilayer can diffuse
laterally, and the rate of diffusion as a proxy for fluidity can be observed using FRAP
experiments. Which of the following changes would lead to longer recovery time from
photobleaching?
O a. Adding more cholesterol to the membrane composition
b. Decreasing cis-double bond content relative to trans-double bond content in the
phospholipids
O c. Increasing unsaturated phospholipid content
O d. Removing membranc-embedded protcins
The lipid bilayer forming cell membranes behaves as a 2D fluid whose fluidity depends largely on its lipid composition.
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