The figure below is taken from Almada et. al. (2013) and depicts the distribution of two sequences (U1 and PAS) near the

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The figure below is taken from Almada et. al. (2013) and depicts the distribution of two sequences (U1 and PAS) near the

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The Figure Below Is Taken From Almada Et Al 2013 And Depicts The Distribution Of Two Sequences U1 And Pas Near The 1
The Figure Below Is Taken From Almada Et Al 2013 And Depicts The Distribution Of Two Sequences U1 And Pas Near The 1 (343.94 KiB) Viewed 233 times
The figure below is taken from Almada et. al. (2013) and depicts the distribution of two sequences (U1 and PAS) near the transcription start site in mammals. b Discriminative hexamer analysis GGUAAG (1st) U1 signal (5' splice site) GGUGAG (3rd) GUGAGU (5th) Log₂ (sense/antisense counts) 0.5- AUUAAA (61st) PAS AAUAAA (1st) 0 1,000 2,000 3,000 4,000 Ranked hexamers • What processes are the two sequences involved in? (2 marks) • What is the significance of one sequence being close to the start site in the sense strand and the other in the antisense strand? (4 marks) • How do yeast and mammals differ in splicing initiation? (2 marks) • What evolutionary feature of higher eukaryotes necessitates this difference? (2 marks) -0.5
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