- The Figure Below Is Taken From Almada Et Al 2013 And Depicts The Distribution Of Two Sequences U1 And Pas Near The 1 (343.94 KiB) Viewed 244 times
The figure below is taken from Almada et. al. (2013) and depicts the distribution of two sequences (U1 and PAS) near the
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The figure below is taken from Almada et. al. (2013) and depicts the distribution of two sequences (U1 and PAS) near the
The figure below is taken from Almada et. al. (2013) and depicts the distribution of two sequences (U1 and PAS) near the transcription start site in mammals. b Discriminative hexamer analysis GGUAAG (1st) U1 signal (5' splice site) GGUGAG (3rd) GUGAGU (5th) Log₂ (sense/antisense counts) 0.5- AUUAAA (61st) PAS AAUAAA (1st) 0 1,000 2,000 3,000 4,000 Ranked hexamers • What processes are the two sequences involved in? (2 marks) • What is the significance of one sequence being close to the start site in the sense strand and the other in the antisense strand? (4 marks) • How do yeast and mammals differ in splicing initiation? (2 marks) • What evolutionary feature of higher eukaryotes necessitates this difference? (2 marks) -0.5
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