1. (A) Which of these fields of study: (1) Genomics (2) Transcriptomics and (3) Proteomics would be most effective for e

[answerhappygod]

1. (A) Which of these fields of study: (1) Genomics (2)
Transcriptomics and (3) Proteomics would be most effective for
elucidating an individual’s susceptibility to a given human
genetic disorder such as Autism or Schizophrenia (you can use a
combination of fields your answer). Hint: Refer to Lecture
“Genomics & Proteomics” to answer this
question.
(B) Which of these fields (Genomics, Transcriptomics,
Proteomics; can be a combination of fields in your answer)
were instrumental in the design of effective COVID RNA
vaccines?
2. Select 3 disorders from the following
selection:
(a) Schizophrenia OR Autism (b) Parkinson’s Disease OR
ALS
(c) Alzheimer’s disease OR Prion
Disease.
(A) Discuss two ways that these disorders are similar to
one another (i.e. what is the mechanism by which they cause
disorder, are they polygenic, etc.). Make certain to include the
prion-based theory for misfolded protein spread.
(B) Discuss two ways these disorders differ from one
another.
(C) Describe how animal and inducible pluripotent stem
cell model systems are helpful for elucidating mechanisms
underlying these disorders.
(D) Should these model systems be used separately or in
conjunction with one another to explore these neurodegenerative
disorders.
3. Why is neuroepigenetic gene regulation critical for
neuroplasticity and cognition? Include in your
discussion:
(A) The definition of what neuroplasticity is and why it
is important in cognition
(B) How neuroplasticity is controlled by neuroepigenetic
gene regulation: include how chromatin writers, readers and erasers
are critical for this process.
(C) Explain how computer games that are “good for your
brain” such as “Luminocity” enhance your cognitive ability. (Hint:
discuss the molecular pathway for how positive external cues are
translated into hard wired changes in the brain via
neuroepigenetics).