A Cisplatin Is Used Widely For The Treatment Of A Variety Of Solid Tumours It Forms Adducts With Cancer Cell Dna That 1 (16.36 KiB) Viewed 47 times
A Cisplatin Is Used Widely For The Treatment Of A Variety Of Solid Tumours It Forms Adducts With Cancer Cell Dna That 2 (16.55 KiB) Viewed 47 times
(a) Cisplatin is used widely for the treatment of a variety of solid tumours. It forms adducts with cancer cell DNA that, if not repaired, can be cytotoxic. Give a short explanation for each of the following observations regarding how Cisplatin targets DNA:
Intra-strand crosslinks between adjacent G bases are most common, intra-strand crosslinks between an A base and a G base are rarer, and inter-strand cross links between G bases are the least common.
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