- 6 Vocabulary 41 Pts Fill In The Blanks With The Appropriate Vocabulary Word S If Multiple Words Are Given Circle 1 (79.49 KiB) Viewed 75 times
6. Vocabulary: (41 pts.) Fill in the blanks with the appropriate vocabulary word(s). If multiple words are given circle the one that best completes the sentence. a. Phenols are more/less/ equally acidic as alcohols. They can / cannot form esters with carboxylic acids and can / cannot form esters with acyl halides. b. The Paal-Knorr synthesis makes a ring from an amine and a a/B/y 18 functional group. The Hantzsch synthesis makes a ring from ammonia, an aldehyde and 1/2/3/other functional group. equivalents of a a/B/y/8 c. N/O/CI has the most resonance with the carbonyl in carboxylic acid derivatives. This gives a faster/slower hydrolysis, a larger / smaller wavenumber IR, a larger / smaller enolate pKa, and a better / worse leaving group. d. can be used to make masked acyl anions and can add a multitude of electrophiles it's pka is can be used as a 'green' catalyst to create masked acyl anions and will always / sometimes / never give products with symmetrical alkyl groups. It can / cannot be deprotonated by NaOH. e. Adding alkyl groups to an amine increases / decreases / doesn't change pKa of the ammonium due to electron donation and increases / decreases / doesn't change pka of the ammonium due to steric hindrance. This makes 1°/2°/3° amines the best bases. f. Which of these will not act as an electrophile for a Malonic Ester Synthesis? epoxides / conjugated ketones / alkyl halides/aldehydes/acyl halides / none g. Heterocycles typically do / do not react like linear forms of the same functional group. The exception is which also react with h. Electrophilic aromatic substitution typically occurs on the pyrrole/benzene / both / neither ring of indole. Nucleophilic aromatic substitution typically occurs on the pyrrole/benzene / both / neither ring of indole. This is because the pyrrole is electron rich / poor. i. Benzyne formation will always / sometimes / never give an ipso phenol. Nucleophilic aromatic substitution will always / sometimes / never give an ipso phenol. j. Claisen Condensations always / sometimes / never use an ester as a nucleophile, always/sometimes / never use a ketone as an electrophile, always / sometimes/ never require the electrophile to have at least 2 alpha-H, and require catalytic / stoichiometric / excess base. k. Benzylic positions react faster/slower / the same as non-benzylic alkyl groups. 1. Carbohydrates are generally NOT used as energy storage/ structure/catalysts. Proteins are generally NOT used as energy storage/ structure/catalysts. m. True/False Ketones are distinct from esters in the IR and in the C NMR. n. True/False Most amines are made via direct alkylation of ammonia.