9. All clinically available carbapenems have low oral bioavailability, thus do not cross gastrointestinal membranes read

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9 All Clinically Available Carbapenems Have Low Oral Bioavailability Thus Do Not Cross Gastrointestinal Membranes Read 1 (18.76 KiB) Viewed 13 times

9. All clinically available carbapenems have low oral bioavailability, thus do not cross gastrointestinal membranes readily and must be administered intravenously. Tebipenem-pivoxil, as shown below, is the world's first oral carbapenem in development. Discribe how it differs from the carbapenems discussed in class. Explain how tebipenem-pivoxil works orally. OH HH (3 marks)