2 1. Consider a ligand that binds to a receptor to form a complex. The association rate constant is given by kf min-' M-

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2 1 Consider A Ligand That Binds To A Receptor To Form A Complex The Association Rate Constant Is Given By Kf Min M 1 (85.39 KiB) Viewed 10 times

2 1. Consider a ligand that binds to a receptor to form a complex. The association rate constant is given by kf min-' M-1, while the dissociation rate constant is given by k; min-1. Assuming that the ligand concentration stays constant at Lo M, and the total number of receptors per cell is a #/cell, derive an expression using Laplace transforms for the number of free receptors per cell as a function of time. Note that there is no ligand in the experiment until t=0. After deriving the expression, please sketch a plot of the number of free receptors per cell as a function of time.