Like A Good Cell Biologist You Decide To Look At C Rulez Cells Under A Microscope And Observe Very Interesting Cell Beh 1 (45.16 KiB) Viewed 48 times
Like A Good Cell Biologist You Decide To Look At C Rulez Cells Under A Microscope And Observe Very Interesting Cell Beh 2 (61.62 KiB) Viewed 48 times
Like a good cell biologist, you decide to look at C.rulez cells under a microscope and observe very interesting cell behavior. The cells send out a protrusive extension that appears to be pushing small pieces of deturis in the extracellular space Intrigued you do some experiments and find a branched actin network in these protrusive extensions that is necessary for this interesting debris herding behavior Debris Protrusion Cell Body Question 21 1 pts Based on what you have learned about cell migration, which statement best explains how the C. rulez cells are pushing the debris around? Choose the ONE BEST answer. Myosin walking on the branched actin pushes the protrusion which pushes the debris forward The branched actin network is using actin-myosin based contracting to create a force to push the debris forward O Retrograde How created by actin polymerization creates a force to push the membrane and this force is also able to push the debris on the outside of the cell Polymerization of branched actin oriented towards the front of the protrusion pushes the membrane forward and this force is also able to push the debris on the outside of the cell
Question 22 1 pts Testing whether these protrusions really do behave just like a lamellipodium, you use a Rac inhibitor and observe that the C. rulez protrusions stop pushing the debris forward and become stationary. Based on what you have learned about cell migration, what is a plausible explanation for what you observe? Choose the ONE BEST answer. O The debris normally inhibits Rho, but Rac inhibition stimulates Rho which promotes the growth of a branched actin network at the front of the protrusion O The debris is normally activating Rac, thereby stimulating the growth of a branched actin etwork at the front of the protrusion O The debris is normally inhibiting Rac. which stimulates the growth of a branched actin network at the front of the protrusion O inhibiting Rac also inhibits Rho, which stimulates the growth of a branched actin network at the front of the protrusion
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