10 E 10+ D A short section of ds 2-DNA (4882 base pairs, bp) has a random coil conformation when it is not stretched, an

[answerhappygod]

10 E 10 D A Short Section Of Ds 2 Dna 4882 Base Pairs Bp Has A Random Coil Conformation When It Is Not Stretched An 1 (96.62 KiB) Viewed 58 times

10 E 10+ D A short section of ds 2-DNA (4882 base pairs, bp) has a random coil conformation when it is not stretched, and a bend persistence length of 150 bp. When the molecule is stretched vertically (along the y-axis) by optical tweezers, force vs. relative extension follows the green line in the plot. a.) First, find the length of an equivalent molecule of B-form DNA. (This is the denominator in the relative extension on the x-axis of the plot.) c 0 force (N) 10° B A 10-11 102 0 2.0 0.5 1.0 1.5 DNA extension/B-form length b.) For the short section molecule of ds 2-DNA find the Kuhn segment length in nm units, and the number of Kuhn segments in the molecule. c.) Now the optical tweezers are applied to the molecule producing the data in the plot. At the relative extension of 0.5, the slope of the graph gives the spring constant as 3.29 x 10* pN/nm. At this extension, what is the root mean square end-to-end distance of the molecule in nm units? a d.) Calculate the probability that the molecule (with one end at the origin) will have the other end a distance away which is equal to the rms distance you found in (c).