10,000 3. Figure 3 - Panel b: S. aureus cultures were grown b 1,000,000 for 30 days with subinhibitory concentrations (a

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10 000 3 Figure 3 Panel B S Aureus Cultures Were Grown B 1 000 000 For 30 Days With Subinhibitory Concentrations A 1 (54.34 KiB) Viewed 190 times

10,000 3. Figure 3 - Panel b: S. aureus cultures were grown b 1,000,000 for 30 days with subinhibitory concentrations (amounts of either antibiotic which are not strong 100,000 enough to kill the bacteria) of either Lugdunin or Rifampicin (an established antibiotic used clinically to treat bacterial infections). At each time point samples of the growing culture tested for to see what the Minimum Inhibitory Concentration (MIC; the minimum dose of an antibiotic needed to kill the cultures - Y axis) was at that point. a) What does Panel b show about the relative risk of antibiotic resistance for Lugdunin compared to something that is already used to treat patients? Fold change in MIC 1.000- 100- Rifampicin Lugdunin 10- 1 0 30 10 20 Time (d) b) How does production of chemicals like Lugdunin by beneficial microbes living on our body surfaces help reduce the amount of work that our immune systems have to do?