(a) Answer all sections (i) – (iv). Below is given the structure of four anti-HIV drugs: NH2 "CF3 co mo komedo que Efavi

[answerhappygod]

A Answer All Sections I Iv Below Is Given The Structure Of Four Anti Hiv Drugs Nh2 Cf3 Co Mo Komedo Que Efavi 1 (206.87 KiB) Viewed 111 times

(a) Answer all sections (i) – (iv). Below is given the structure of four anti-HIV drugs: NH2 "CF3 co mo komedo que Efavirenz Adefovir dipivoxil HO es HO OH CONH2 Elvitegravir Saqunavir i) Give the drug target for each of these four drugs. (20) Suggest another possible drug target from the HIV virus to which there is still no commercial drug developed (5 III) Discuss the mechanism behind the anti-HIV effect of Efavirenz? (10) Adefovir dipivoxil is a prodrug. Show schematically how it is converted to the active drug (including the structure of the latter). (15) Answer all sections (1) - (iv). Draw the structure of muramic acid and indicate where it is linked to other saccharides and to a peptide when part of the bacteria cell wall peptidoglycan. (15)