Questions: Does cancer require 1 mutation to start or an accumulation of several gene mutations? Explain. 2. Are most ca

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Questions:
Does cancer require 1 mutation to start or an accumulation of
several gene mutations? Explain.
2. Are most cancers inherited from our parents? Explain
3. How do most chemo-therapies work?
4. How is Gleevec different?
5. What is the function of a proto-oncogene?
6. How do oncogenes differ from proto-oncogenes?
7. Which is normal / cancer - causing: proto-oncogene or
oncogene?
8. Give an example of a proto-oncogene: ____________
9. It usually takes ________ different genetic mutations over
many years for cancer to develop.
10. What is the function of a tumor suppressor gene?
11. Which tumor suppressor gene is called the "guardian angel"
of the cell?
12. What job does the product of the "guardian angel gene" have
in the cell?
13. Damage to a cell's DNA leads to an increase / decrease in
the amount of p53 protein in the cell.
14. P53 is a ________ that works in several ways to make sure
that damaged DNA is not replicated.
15. The path to cancer often begins with mutations in __________
genes
16. Why is a woman with an inherited mutation in the BRCA1 /
BRCA2 gene more likely to develop cancer?
17. What are Cell Cycle Checkpoints? what do they "Check"
for?
18. What is a telomere?
19. What happens to the telomere as the cell divides?
20. Give 3 examples of cells that must replicate endlessly.
21. What allows these cells to continue to divide?
22. What happens to cancer cells that allows them to continue to
divide?
23. What is angiogenesis?
24. Without scientific treatments and cures, how could half of
cancer in the United States be prevented?