‘Mutations in the dystrophin (DMD) gene cause the almost complete loss of the Dp427-M isoform of dystrophin, which trigg

[answerhappygod]

‘Mutations in the dystrophin (DMD) gene cause the almost
complete loss of the Dp427-M isoform of dystrophin, which triggers
complex pathophysiological alterations in X-linked muscular
dystrophy’. Discuss this statement and outline the major role of
dystrophin within the skeletal muscle surface membrane system. In
your answer, describe in detail how its loss may render muscle
fibres more susceptible to necrosis, reactive myofibrosis and
sterile inflammation. You may support your answer with hand-drawn
diagrams.
essay style question please