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3. Explain the logic in the retrosynthetic analysis in Scheme 1B Scheme 1. Retrosynthetic Analysis of (+)-Clavilactone A
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3. Explain the logic in the retrosynthetic analysis in Scheme 1B Scheme 1. Retrosynthetic Analysis of (+)-Clavilactone A
3. Explain the logic in the retrosynthetic analysis in Scheme 1B Scheme 1. Retrosynthetic Analysis of (+)-Clavilactone A (1) A) ring-opening/ring-closing metathesis (ROM/RCM) RCM ROM 7m catalyst R R x X = CH2, NR, O B) retrosynthetic analysis of (+)-clavilactone A (1) Me ОMe RCM Me OH ОMe OH (+)-Clavilactone A (1) ОMe Br ОMe Br ROMRCM OMe o OMe 90 8 ОMe Br + HO OM OH 10 11