Mrs. EB visited her GP to discuss symptoms including irregularity in her menstrual periods, hot flushes, and night sweat

[answerhappygod]

Mrs. EB visited her GP to discuss symptoms including
irregularity in her
menstrual periods, hot flushes, and night sweats. She also has
experienced some
anxiety issues and mood changes and is no longer sleeping well
a) What do you think maybe responsible for her symptoms?
Her GP suggested she may be suffering menopausal symptoms and had
a
conversation with her about HRT.
b) Place yourself in the role of her GP and discuss the
indications,
advantages, disadvantages, and precautions with the use of combined
estrogen–
progestogen HRT during menopause.
c) With your knowledge of estrogen receptors discuss designing a
novel drug
with estrogenic activity that maximized responses on the
reproductive tract
but minimized the responses on the cardiovascular system,