Question 22 3 pts Considering the three molecules shown to the right. V and VI are variants of combrestatin. Why is it t
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Question 22 3 pts Considering the three molecules shown to the right. V and VI are variants of combrestatin. Why is it t
Question 22 3 pts Considering the three molecules shown to the right. V and VI are variants of combrestatin. Why is it that analog V is more active than analog VI and combretastatin? H.CO. H₂CO OH OCH₂ Combretastatin OCH₂ H.CO. H.CO a 'OH OCH, V H,CO хос H,CO V O Combretastatin is has an additional hydrogen bonding group. O Analog Vis locked in the active conformation O Analog VI has less entropy than analog V. Analog V has more entropy than combretastatin OCH,
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