5. a) Which of the following reaction(s) does not require protonation of the carbonyl oxygen? (4) points) NaBH₁ oi a. H₂

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5 A Which Of The Following Reaction S Does Not Require Protonation Of The Carbonyl Oxygen 4 Points Nabh Oi A H 1 (32.78 KiB) Viewed 42 times

5. a) Which of the following reaction(s) does not require protonation of the carbonyl oxygen? (4) points) NaBH₁ oi a. H₂O b. i CH,MgBr CH,OH d. b) The reason that the carbonyl oxygen does not have to be protonated is (4 points): i. Ketones are the most electrophilic of carbonyl compounds. ii. Strong nucleophiles are reactive enough that the carbonyl does not have to be made more electrophilic. iii. Strong nucleophiles are so reactive that the carbonyl has to be protected by protonating it. iv. Ketones are more reactive than aldehydes in nucleophilic addition reactions.