Question 2 The drug amoxycillin is formulated in different dosage forms such “Amoxil Parenteral” from Aspen and the prod

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Question 2
The drug amoxycillin is formulated in different dosage forms
such “Amoxil Parenteral” from Aspen and the product “Amoxycillin
Sandoz Powder for Suspension”. Answer the following related
questions about these products:
A. Discuss the rationale of formulating the drug amoxycillin as
powder for injection (in “Amoxil Parenteral”) rather than prepared
injection. [2 marks]
B. It is likely that the drug amoxycillin in the product “Amoxil
Parenteral” is lyophilised. Explain the term “lyophilisation” and
the need to prepare the drug in this form for this product. [2
marks]
C. Outline TWO excipients used in the product “Amoxycillin
Sandoz Powder for Suspension” and the function of each excipient.
[2 marks]
D. Using the physicochemical properties of the drug (in the salt
used in formulation), explain why the product “Amoxycillin Sandoz
Powder for Suspension” is administered as suspension rather than
solution and how this is different from the product: “Amoxil
Parenteral”. [2 marks]