Which of the followings is the negative selection method in T-cell central tolerance? a. T cells that display the ho

[answerhappygod]

Which of the followings is the negative selection method in
T-cell central tolerance?
a. T cells that display the host’s MHC antigen
and T-cell receptors for a nonself-antigen are allowed to mature in
the thymus
b. T cells that have a high affinity for host
cells are sorted out and undergo apoptosis or cell
death
c. The host antigens are sequestered from the
self-reactive T cells
d. Absence of the costimulatory signals for the
self-reactive T cells