A 26-year-old man presented urgently, complaining of muscle pains. He had been found to have heterozygous familial hyper
Posted: Fri Aug 26, 2022 10:02 am
A 26-year-old man presented urgently, complaining of muscle pains. He had been found to have heterozygous familial hypercholesterolaemia 2 years previously owing to a mutation in the PCSK9 gene. He had a strong family history of premature vascular disease. He was taking atorvastatin 80 mg daily.Investigations:serum creatine kinase2782 U/L (24195)serum cholesterol5.7 mmol/L (<5.2)After stopping atorvastatin, his serum creatine kinase fell to within the normal range.What is the most appropriate next step in management?
A. restart atorvastatin 10 mg
B. restart atorvastatin 40 mg
C. start ezetimibe 10 mg
D. start fenofibrate 100 mg E. start fluvastatin 40 mg
A. restart atorvastatin 10 mg
B. restart atorvastatin 40 mg
C. start ezetimibe 10 mg
D. start fenofibrate 100 mg E. start fluvastatin 40 mg